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Regulation of the Virulence Determinant OspC by bbd18 on Linear Plasmid lp17 of Borrelia burgdorferi

Persistent infection of a mammalian host by Borrelia burgdorferi, the spirochete that causes Lyme disease, requires specific downregulation of an immunogenic outer surface protein, OspC. Although OspC is an essential virulence factor needed by the spirochete to establish infection in the mammal, it...

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Autori principali: Sarkar, Amit, Hayes, Beth M., Dulebohn, Daniel P., Rosa, Patricia A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187453/
https://ncbi.nlm.nih.gov/pubmed/21784941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01496-10
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