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Novel Hemin Binding Domains in the Corynebacterium diphtheriae HtaA Protein Interact with Hemoglobin and Are Critical for Heme Iron Utilization by HtaA
The human pathogen Corynebacterium diphtheriae utilizes hemin and hemoglobin as iron sources for growth in iron-depleted environments. The use of hemin iron in C. diphtheriae involves the dtxR- and iron-regulated hmu hemin uptake locus, which encodes an ABC hemin transporter, and the surface-anchore...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3187408/ https://ncbi.nlm.nih.gov/pubmed/21803991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.05508-11 |
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