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Serine/Threonine Protein Kinase Stk Is Required for Virulence, Stress Response, and Penicillin Tolerance in Streptococcus pyogenes

Genes encoding one or more Ser/Thr protein kinases have been identified recently in many bacteria, including one (stk) in the human pathogen Streptococcus pyogenes (group A streptococcus [GAS]). We report that in GAS, stk is required to produce disease in a murine myositis model of infection. Using...

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Detalhes bibliográficos
Main Authors: Bugrysheva, Julia, Froehlich, Barbara J., Freiberg, Jeffrey A., Scott, June R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187266/
https://ncbi.nlm.nih.gov/pubmed/21788381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05360-11
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