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The Burkholderia pseudomallei Δasd Mutant Exhibits Attenuated Intracellular Infectivity and Imparts Protection against Acute Inhalation Melioidosis in Mice

Burkholderia pseudomallei, the cause of serious and life-threatening diseases in humans, is of national biodefense concern because of its potential use as a bioterrorism agent. This microbe is listed as a select agent by the CDC; therefore, development of vaccines is of significant importance. Here,...

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Main Authors: Norris, Michael H., Propst, Katie L., Kang, Yun, Dow, Steven W., Schweizer, Herbert P., Hoang, Tung T.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187240/
https://ncbi.nlm.nih.gov/pubmed/21807903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.05044-11
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