The Biofilm Inhibitor Carolacton Disturbs Membrane Integrity and Cell Division of Streptococcus mutans through the Serine/Threonine Protein Kinase PknB

Carolacton, a secondary metabolite isolated from the myxobacterium Sorangium cellulosum, disturbs Streptococcus mutans biofilm viability at nanomolar concentrations. Here we show that carolacton causes leakage of cytoplasmic content (DNA and proteins) in growing cells at low pH and provide quantitat...

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Bibliografiset tiedot
Päätekijät: Reck, Michael, Rutz, Katrin, Kunze, Brigitte, Tomasch, Jürgen, Surapaneni, Subhash Kumar, Schulz, Stefan, Wagner-Döbler, Irene
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2011
Aiheet:
Signal Transduction
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187222/
https://ncbi.nlm.nih.gov/pubmed/21840978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.05424-11
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