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Adjunctive Rifampin Is Crucial to Optimizing Daptomycin Efficacy against Rabbit Prosthetic Joint Infection Due to Methicillin-Resistant Staphylococcus aureus

Daptomycin is an attractive option for treating prosthetic joint infection, but the 6-mg/kg of body weight/day dose was linked to clinical failure and emergence of resistance. Using a methicillin-resistant Staphylococcus aureus (MRSA) knee prosthesis infection in rabbits, we studied the efficacies o...

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Detalhes bibliográficos
Main Authors: Saleh-Mghir, Azzam, Muller-Serieys, Claudette, Dinh, Aurélien, Massias, Laurent, Crémieux, Anne-Claude
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186998/
https://ncbi.nlm.nih.gov/pubmed/21825285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00675-11
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