Human Cellular Immune Response to the Saliva of Phlebotomus papatasi Is Mediated by IL-10-Producing CD8+ T Cells and Th1-Polarized CD4+ Lymphocytes

BACKGROUND: The saliva of sand flies strongly enhances the infectivity of Leishmania in mice. Additionally, pre-exposure to saliva can protect mice from disease progression probably through the induction of a cellular immune response. METHODOLOGY/PRINCIPAL FINDINGS: We analysed the cellular immune r...

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Autors principals: Abdeladhim, Maha, Ben Ahmed, Mélika, Marzouki, Soumaya, Belhadj Hmida, Nadia, Boussoffara, Thouraya, Belhaj Hamida, Nabil, Ben Salah, Afif, Louzir, Hechmi
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186761/
https://ncbi.nlm.nih.gov/pubmed/21991402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001345
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