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Optimization of Data-Dependent Parameters for LC-MS/MS Protein Identification

A typical bottom-up protein identification workflow involves proteolytic digestion followed by identification of the resulting peptides by LC-MS/MS using data-dependent acquisition (DDA). Recent developments in chromatography, such as uHPLC and superficially porous Fused-core particles, offer signif...

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Detalles Bibliográficos
Autores principales: Orlando, R., Johnson, D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Association of Biomolecular Resource Facilities 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186459/
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