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Activating Transcription Factor-6 (ATF6) Mediates Apoptosis with Reduction of Myeloid Cell Leukemia Sequence 1 (Mcl-1) Protein via Induction of WW Domain Binding Protein 1

Endoplasmic reticulum (ER) stress is involved in both physiological and pathological apoptosis. ER stress triggers the unfolded protein response (UPR), which can then initiate apoptosis, when the cell fails to restore ER homeostasis. However, the mechanism employed by the UPR to lead cells into apop...

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Sonraí Bibleagrafaíochta
Main Authors: Morishima, Nobuhiro, Nakanishi, Keiko, Nakano, Akihiko
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186435/
https://ncbi.nlm.nih.gov/pubmed/21841196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.233502
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