Loading...
Lysosomal Storage Causes Cellular Dysfunction in Mucolipidosis II Skin Fibroblasts
Mucolipidosis II (ML-II) is a fatal inherited metabolic disease caused by deficiency of GlcNAc-phosphotransferase, which plays a role in generating the mannose 6-phosphate recognition marker on lysosomal enzymes. In ML-II, many lysosomal acid hydrolases are mistargeted out of cells, and lysosomes be...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3186395/ https://ncbi.nlm.nih.gov/pubmed/21846724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.267930 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|