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Alternative sites of transcription initiation upstream of the canonical cap site in human gamma-globin and beta-globin genes.

Using S1 mapping and primer extension analysis, we have identified a number of human kappa-globin and beta-globin 5' RNA termini originating in the 200 bp upstream of the canonical mRNA cap sites. Upstream initiation sites have previously been reported for the human epsilon-globin gene (4,5) an...

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Bibliographic Details
Main Authors: Grindlay, G J, Lanyon, W G, Allan, M, Paul, J
Format: Artigo
Language:Inglês
Published: 1984
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC318622/
https://ncbi.nlm.nih.gov/pubmed/6701091
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