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GSK3 controls axon growth via CLASP-mediated regulation of growth cone microtubules

Suppression of glycogen synthase kinase 3 (GSK3) activity in neurons yields pleiotropic outcomes, causing both axon growth promotion and inhibition. Previous studies have suggested that specific GSK3 substrates, such as adenomatous polyposis coli (APC) and collapsin response mediator protein 2 (CRMP...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hur, Eun-Mi, Saijilafu, Lee, Byoung Dae, Kim, Seong-Jin, Xu, Wen-Lin, Zhou, Feng-Quan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185968/
https://ncbi.nlm.nih.gov/pubmed/21937714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.17015911
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