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Cdc15 integrates Tem1 GTPase-mediated spatial signals with Polo kinase-mediated temporal cues to activate mitotic exit

In budding yeast, a Ras-like GTPase signaling cascade known as the mitotic exit network (MEN) promotes exit from mitosis. To ensure the accurate execution of mitosis, MEN activity is coordinated with other cellular events and restricted to anaphase. The MEN GTPase Tem1 has been assumed to be the cen...

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Detalhes bibliográficos
Main Authors: Rock, Jeremy M., Amon, Angelika
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185966/
https://ncbi.nlm.nih.gov/pubmed/21937712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.17257711
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