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The crystal structure of an oligo(U):pre-mRNA duplex from a trypanosome RNA editing substrate

Guide RNAs bind antiparallel to their target pre-mRNAs to form editing substrates in reaction cycles that insert or delete uridylates (Us) in most mitochondrial transcripts of trypanosomes. The 5′ end of each guide RNA has an anchor sequence that binds to the pre-mRNA by base-pair complementarity. T...

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Hlavní autoři: Mooers, Blaine H.M., Singh, Amritanshu
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185919/
https://ncbi.nlm.nih.gov/pubmed/21878548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2880311
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