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Metabolic and perfusion responses to recurrent peri-infarct depolarization during focal ischemia in the Spontaneously Hypertensive Rat: dominant contribution of sporadic CBF decrements to infarct expansion

Peri-infarct depolarizations (PIDs) contribute to the evolution of focal ischemic lesions. Proposed mechanisms include both increased metabolic demand under conditions of attenuated perfusion and overt vasoconstrictive responses to depolarization. The present studies investigated the relative contri...

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Hlavní autoři: Takeda, Yoshimasa, Zhao, Liang, Jacewicz, Michael, Pulsinelli, William A, Nowak, Thaddeus S
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185883/
https://ncbi.nlm.nih.gov/pubmed/21522165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.62
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