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The Dynactin Complex Enhances the Speed of Microtubule-Dependent Motions of Adenovirus Both Towards and Away from the Nucleus

Unlike transport vesicles or organelles, human adenovirus (HAdV) directly binds to the microtubule minus end-directed motor dynein for transport to the nucleus. The dynein cofactor dynactin enhances nuclear transport of HAdV and boosts infection. To determine if dynactin has a specific role in cytop...

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Detalhes bibliográficos
Main Authors: Engelke, Martin F., Burckhardt, Christoph J., Morf, Matthias K., Greber, Urs F.
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185697/
https://ncbi.nlm.nih.gov/pubmed/21994728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v3030233
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