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Lentiviral Vectors and Cystic Fibrosis Gene Therapy
Cystic fibrosis (CF) is a chronic autosomic recessive syndrome, caused by mutations in the CF Transmembrane Conductance Regulator (CFTR) gene, a chloride channel expressed on the apical side of the airway epithelial cells. The lack of CFTR activity brings a dysregulated exchange of ions and water th...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Molecular Diversity Preservation International (MDPI)
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3185599/ https://ncbi.nlm.nih.gov/pubmed/21994643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v2020395 |
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