Adenosine deaminase (ADA) deficiency in cells derived from humans with severe combined immunodeficiency is due to an aberration of the ADA protein.

In order to determine the molecular basis of adenosine deaminase (ADA) deficiency in cells derived from patients with severe combined immunodeficiency (SCID) disease, we used a human ADA cDNA clone (1) to analyse the organization and transcription of the ADA gene in both normal and ADA-SCID cells. I...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Valerio, D, Duyvesteyn, M G, van Ormondt, H, Meera Khan, P, van der Eb, A J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1984
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC318552/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6198631/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/12.2.1015
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