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Ubiquitination of human AP-endonuclease 1 (APE1) enhanced by T233E substitution and by CDK5
Apurinic/apyrimidinic endonuclease-1 (APE1) is a multifunctional DNA repair/gene regulatory protein in mammalian cells, and was recently reported to be phosphorylated at Thr233 by CDK5. We here report that ubiquitination of T233E APE1, a mimicry of phospho-T233 APE1, was markedly increased in multip...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3185409/ https://ncbi.nlm.nih.gov/pubmed/21727086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr401 |
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