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c-Rel Deficiency Increases Caspase-4 Expression and Leads to ER Stress and Necrosis in EBV-Transformed Cells
LMP1-mediated activation of nuclear factor of kappaB (NF-κB) is critical for the ligand independent proliferation and cell survival of in vitro EBV-transformed lymphoblastoid cell lines (LCLs). Previous experiments revealed that a majority of LMP1-dependent responses are regulated by NF-κB. However,...
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Main Authors: | , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Public Library of Science
2011
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3184984/ https://ncbi.nlm.nih.gov/pubmed/21984918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025467 |
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