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Direct Fmoc-Chemistry-Based Solid Phase Synthesis of Peptidyl Thioesters
[Image: see text] Attachment of a growing peptide chain to a glycylaminomethyl resin via a thioglycinamide bond is compatible with Fmoc-chemistry solid phase peptide synthesis. Subsequent S-alkylation of the thioamide gives a thioimide which, on treatment with aqueous trifluoroacetic acid releases t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3184774/ https://ncbi.nlm.nih.gov/pubmed/21718046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo200497j |
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