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NRPS Substrate Promiscuity Diversifies the Xenematides
[Image: see text] Xenematide, a cyclic depsipeptide antibiotic produced by Xenorhabdus nematophila, had a candidate nonribosomal peptide synthetase (NRPS) with atypical features. Differential metabolite analysis between a mutant and wildtype validated that this stand-alone NRPS was required for xene...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical Society
2011
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3184645/ https://ncbi.nlm.nih.gov/pubmed/21888371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol2020237 |
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