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Design and Synthesis of Small Molecule Glycerol 3-Phosphate Acyltransferase Inhibitors
The incidence of obesity and other diseases associated with an increased triacylglycerol mass is growing rapidly, particularly in the United States. Glycerol 3-phosphate acyltransferase (GPAT) catalyzes the rate-limiting step of glycerolipid biosynthesis, the acylation of glycerol 3-phosphate with s...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3184552/ https://ncbi.nlm.nih.gov/pubmed/19388675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm900251a |
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