Loss of SPEF2 Function in Mice Results in Spermatogenesis Defects and Primary Ciliary Dyskinesia

Primary ciliary dyskinesia (PCD) results from defects in motile cilia function. Mice homozygous for the mutation big giant head (bgh) have several abnormalities commonly associated with PCD, including hydrocephalus, male infertility, and sinusitis. In the present study, we use a variety of histopath...

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Detalhes bibliográficos
Main Authors: Sironen, Anu, Kotaja, Noora, Mulhern, Howard, Wyatt, Todd A., Sisson, Joseph H., Pavlik, Jacqueline A., Miiluniemi, Mari, Fleming, Mark D., Lee, Lance
Formato: Artigo
Idioma:Inglês
Publicado em: Society for the Study of Reproduction, Inc. 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184289/
https://ncbi.nlm.nih.gov/pubmed/21715716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.111.091132
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