PET imaging of early response to the tyrosine kinase inhibitor ZD4190

PURPOSE: We evaluated noninvasive positron emission tomography (PET) imaging for monitoring tumor response to the VEGFR-2 tyrosine kinase (TK) inhibitor ZD4190 during cancer therapy. EXPERIMENTAL DESIGN: Orthotopic MDA-MB-435 tumor-bearing mice were treated with ZD4190 (100 mg/kg orally per day for...

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Bibliographic Details
Main Authors:	Yang, Min, Gao, Haokao, Yan, Yongjun, Sun, Xilin, Chen, Kai, Quan, Qimeng, Lang, Lixin, Kiesewetter, Dale, Niu, Gang, Chen, Xiaoyuan
Format:	Artigo
Language:	Inglês
Published:	2011
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3184245/ https://ncbi.nlm.nih.gov/pubmed/21360246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-011-1742-z
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PET imaging of early response to the tyrosine kinase inhibitor ZD4190

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