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Treatment benefit or survival of the fittest: what drives the time-dependent decrease in serious infection rates under TNF inhibition and what does this imply for the individual patient?

OBJECTIVE: To examine the risk of serious infection conveyed by tumour necrosis factor α (TNFα) inhibitors in the treatment of rheumatoid arthritis (RA). METHODS: Data from patients with RA enrolled in the German biologics register RABBIT were used for analysis. Baseline patient characteristics, tim...

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Autors principals: Strangfeld, A, Eveslage, M, Schneider, M, Bergerhausen, H J, Klopsch, T, Zink, A, Listing, J
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184240/
https://ncbi.nlm.nih.gov/pubmed/21791449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2011.151043
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