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Role of β4 integrin phosphorylation in human invasive squamous cell carcinoma: regulation of hemidesmosome stability modulates cell migration

Hemidesmosomes (HDs) are multiprotein structures that anchor epithelia to the basement membrane. During squamous cell carcinoma (SCC) invasion there is a reduction in the number of HDs, which may facilitate dissemination. Mechanisms of HD disassembly are incompletely understood. Previous work has sh...

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Detalhes bibliográficos
Main Authors: Kashyap, Trinayan, Germain, Emily, Roche, Michael, Lyle, Stephen, Rabinovitz, Isaac
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184203/
https://ncbi.nlm.nih.gov/pubmed/21769085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2011.104
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