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Unexpected effects on bacterial phenotype induced by expression of a tumour-amplified human sequence.
An amplified human sequence was isolated from a metastatic human lung carcinoma. A fragment of this sequence situated behind the lac promoter of pUC19 appeared to affect plasmid DNA supercoiling in certain E. coli strains. Subclones were constructed to identify the smallest region of the human inser...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
1989
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC318420/ https://ncbi.nlm.nih.gov/pubmed/2476724 |
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