Cdk5 Is Required for Memory Function and Hippocampal Plasticity via the cAMP Signaling Pathway

Memory formation is modulated by pre- and post-synaptic signaling events in neurons. The neuronal protein kinase Cyclin-Dependent Kinase 5 (Cdk5) phosphorylates a variety of synaptic substrates and is implicated in memory formation. It has also been shown to play a role in homeostatic regulation of...

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Detalhes bibliográficos
Main Authors: Guan, Ji-Song, Su, Susan C., Gao, Jun, Joseph, Nadine, Xie, Zhigang, Zhou, Ying, Durak, Omer, Zhang, Lei, Zhu, J. Julius, Clauser, Karl R., Carr, Steven A., Tsai, Li-Huei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184170/
https://ncbi.nlm.nih.gov/pubmed/21984943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025735
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