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Astrotricoumarin, an antiproliferative 4′-hydroxy-2′,3′-dihydroprenylated methylcoumarin from an Astrotrichilia sp. from the Madagascar Dry Forest[1]

Bioassay guided fractionation of the ethanol extract of a new endemic species of the genus Astrotrichilia led to the isolation of the new antiproliferative 3-(4′-hydroxy-2′,3′-dihydroprenyl)-4,6-dimethoxy-5-methylcoumarin, named astrotricoumarin (8) with an IC(50) value of 6.8 μM against the A2780 c...

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Autors principals: Harinantenaina, Liva, Brodie, Peggy J., Callmander, Martin W., Randrianaivo, Richard, Rakotonandrasana, Stephan, Rasamison, Vincent E., Rakotobe, Etienne, Kingston, David G. I.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183991/
https://ncbi.nlm.nih.gov/pubmed/21941893
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