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PITX2 Is Involved in Stress Response in Cultured Human Trabecular Meshwork Cells through Regulation of SLC13A3

PURPOSE. Mutations of the PITX2 gene cause Axenfeld-Rieger syndrome (ARS) and glaucoma. In this study, the authors investigated genes directly regulated by the PITX2 transcription factor to gain insight into the mechanisms underlying these disorders. METHODS. RNA from nonpigmented ciliary epithelium...

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Detalhes bibliográficos
Main Authors: Strungaru, M. Hermina, Footz, Tim, Liu, Yi, Berry, Fred B., Belleau, Pascal, Semina, Elena V., Raymond, Vincent, Walter, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183983/
https://ncbi.nlm.nih.gov/pubmed/21873665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6967
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