The TAg-RB Murine Retinoblastoma Cell of Origin Has Immunohistochemical Features of Differentiated Müller Glia with Progenitor Properties

PURPOSE. Human retinoblastoma arises from an undefined developing retinal cell after inactivation of RB1. This is emulated in a murine retinoblastoma model by inactivation of pRB by retinal-specific expression of simian virus 40 large T-antigen (TAg-RB). Some mutational events after RB1 loss in huma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pajovic, Sanja, Corson, Timothy W., Spencer, Clarellen, Dimaras, Helen, Orlic-Milacic, Marija, Marchong, Mellone N., To, Kwong-Him, Thériault, Brigitte, Auspitz, Mark, Gallie, Brenda L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Association for Research in Vision and Ophthalmology, Inc. 2011
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183982/
https://ncbi.nlm.nih.gov/pubmed/21862643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-7989
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg