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Roles for Cardiac MyBP-C in Maintaining Myofilament Lattice Rigidity and Prolonging Myosin Cross-Bridge Lifetime

We investigated the influence of cardiac myosin binding protein-C (cMyBP-C) and its constitutively unphosphorylated status on the radial and longitudinal stiffnesses of the myofilament lattice in chemically skinned myocardial strips of the following mouse models: nontransgenic (NTG), effective null...

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Main Authors: Palmer, Bradley M., Sadayappan, Sakthivel, Wang, Yuan, Weith, Abbey E., Previs, Michael J., Bekyarova, Tanya, Irving, Thomas C., Robbins, Jeffrey, Maughan, David W.
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183797/
https://ncbi.nlm.nih.gov/pubmed/21961592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.08.047
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