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Local Conformational Flexibility Provides a Basis for Facile Polymer Formation in Human Neuroserpin
Neuroserpin is a regulator of neuronal growth and plasticity. Like other members of the serpin family, neuroserpin undergoes a large conformational change as part of its function. Unlike other serpins such as α(1)-antitrypsin, wild-type neuroserpin will polymerize under near-physiological conditions...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3183757/ https://ncbi.nlm.nih.gov/pubmed/21961602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.08.037 |
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