Essential Role for Vav Guanine Nucleotide Exchange Factors in Brain-Derived Neurotrophic Factor-Induced Dendritic Spine Growth and Synapse Plasticity

Brain-derived neurotrophic factor (BDNF) and its cognate receptor, TrkB, regulate a wide range of cellular processes, including dendritic spine formation and functional synapse plasticity. However, the signaling mechanisms that link BDNF-activated TrkB to F-actin remodeling enzymes and dendritic spi...

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Detalhes bibliográficos
Main Authors: Hale, Carly F., Dietz, Karen C., Varela, Juan A., Wood, Cody B., Zirlin, Benjamin C., Leverich, Leah S., Greene, Robert W., Cowan, Christopher W.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183742/
https://ncbi.nlm.nih.gov/pubmed/21880903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0685-11.2011
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