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Aberrant expression of platelet-derived growth factor A-chain cDNAs due to cryptic splicing of RNA transcripts in COS-1 cells.

Platelet-derived growth factor (PDGF) is a cationic dimer composed of two chains, designated A and B. All three dimeric isotypes of PDGF, PDGF-AA, -AB and -BB, are biologically active but may have distinct functional activities. Two A-chain precursors which differ by the presence of a highly basic 1...

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Bibliographic Details
Main Authors: Wise, R J, Orkin, S H, Collins, T
Format: Artigo
Language:Inglês
Published: 1989
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC318352/
https://ncbi.nlm.nih.gov/pubmed/2780289
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