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Identification of a mechanochemical checkpoint and negative feedback loop regulating branching morphogenesis
Cleft formation is the initial step in submandibular salivary gland (SMG) branching morphogenesis, and may result from localized actomyosin-mediated cellular contraction. Since ROCK regulates cytoskeletal contraction, we investigated the effects of ROCK inhibition on mouse SMG ex vivo organ cultures...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3183484/ https://ncbi.nlm.nih.gov/pubmed/19804774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.09.037 |
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