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Identification of a mechanochemical checkpoint and negative feedback loop regulating branching morphogenesis

Cleft formation is the initial step in submandibular salivary gland (SMG) branching morphogenesis, and may result from localized actomyosin-mediated cellular contraction. Since ROCK regulates cytoskeletal contraction, we investigated the effects of ROCK inhibition on mouse SMG ex vivo organ cultures...

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Detalhes bibliográficos
Main Authors: Daley, William P., Gulfo, Kathryn M., Sequeira, Sharon J., Larsen, Melinda
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183484/
https://ncbi.nlm.nih.gov/pubmed/19804774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2009.09.037
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