Dihydrophenylalanine: A prephenate-derived Photorhabdus luminescens antibiotic and intermediate in dihydrostilbene biosynthesis

2,5-Dihydrophenylalanine (H(2)Phe) is a multi-potent non-proteinogenic amino acid produced by various Actinobacteria and Gammaproteobacteria. While the metabolite was discovered over forty years ago, details of its biosynthesis have remained largely unknown. We show here that L-H(2)Phe is a secreted...

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Bibliografiske detaljer
Main Authors: Crawford, Jason M., Mahlstedt, Sarah A., Malcolmson, Steven J., Clardy, Jon, Walsh, Christopher T.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183431/
https://ncbi.nlm.nih.gov/pubmed/21944749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.07.009
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