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Nrf2 protects against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced oxidative injury and steatohepatitis

Previous studies demonstrate that Nrf2, a master regulator of antioxidative responses, is essential in mediating induction of many antioxidative enzymes by acute activation of the AhR. However, the role of Nrf2 in protecting against oxidative stress and DNA damage induced by sustained activation of...

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Detalhes bibliográficos
Main Authors: Lu, Hong, Cui, Wei, Klaassen, Curtis D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183285/
https://ncbi.nlm.nih.gov/pubmed/21846477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2011.07.019
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