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Ceruloplasmin Protects Against Rotenone-Induced Oxidative Stress and Neurotoxicity

To clarify the neuroprotective property of ceruloplasmin and the pathogenesis of aceruloplasminemia, we generated ceruloplasmin-deficient (CP (−/−)) mice on the C57BL/10 genetic background and further treated them with a mitochondrial complex I inhibitor, rotenone. There was no iron accumulation in...

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Autori principali: Hineno, Akiyo, Kaneko, Kazuma, Yoshida, Kunihiro, Ikeda, Shu-ichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183265/
https://ncbi.nlm.nih.gov/pubmed/21706374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-011-0537-8
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