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Functional Restoration of Critically Sized Segmental Defects With Bone Morphogenetic Protein-2 and Heparin Treatment

BACKGROUND: Bone defects and fracture nonunions remain a substantial challenge for clinicians. Grafting procedures are limited by insufficient volume and donor site morbidity. As an alternative, biomaterial scaffolds functionalized through incorporation of growth factors such as bone morphogenetic p...

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Detalhes bibliográficos
Main Authors: Johnson, Mela R., Boerckel, Joel D., Dupont, Kenneth M., Guldberg, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183200/
https://ncbi.nlm.nih.gov/pubmed/21863396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11999-011-2012-x
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