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Presynaptic Regulation of Quantal Size: K(+)/H(+) Exchange Stimulates Glutamate Storage by Increasing Membrane Potential

The amount of neurotransmitter stored in a single synaptic vesicle can determine the size of the postsynaptic response, but the factors that regulate vesicle filling remain poorly understood. A proton electrochemical gradient (Δμ(H+)) generated by the vacuolar H(+)-ATPase drives the accumulation of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Goh, Germaine Y., Huang, Hai, Ullman, Julie, Borre, Lars, Hnasko, Thomas S., Trussell, Laurence O., Edwards, Robert H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183113/
https://ncbi.nlm.nih.gov/pubmed/21874016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2898
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