A Conserved PHD Finger Protein and Endogenous RNAi Modulate Insulin Signaling in Caenorhabditis elegans

Insulin signaling has a profound effect on longevity and the oxidative stress resistance of animals. Inhibition of insulin signaling results in the activation of DAF-16/FOXO and SKN-1/Nrf transcription factors and increased animal fitness. By studying the biological functions of the endogenous RNA i...

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Hlavní autoři: Mansisidor, Andres R., Cecere, Germano, Hoersch, Sebastian, Jensen, Morten B., Kawli, Trupti, Kennedy, Lisa M., Chavez, Violeta, Tan, Man-Wah, Lieb, Jason D., Grishok, Alla
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183084/
https://ncbi.nlm.nih.gov/pubmed/21980302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002299
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