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A phosphatase threshold sets the level of Cdk1 activity in early mitosis in budding yeast
Entry into mitosis is initiated by synthesis of cyclins, which bind and activate cyclin-dependent kinase 1 (Cdk1). Cyclin synthesis is gradual, yet activation of Cdk1 occurs in a stepwise manner: a low level of Cdk1 activity is initially generated that triggers early mitotic events, which is followe...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3183015/ https://ncbi.nlm.nih.gov/pubmed/21849476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-04-0340 |
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