The Human Papillomavirus E6 Oncogene Represses a Cell Adhesion Pathway and Disrupts Focal Adhesion through Degradation of TAp63β upon Transformation

Cervical carcinomas result from cellular transformation by the human papillomavirus (HPV) E6 and E7 oncogenes which are constitutively expressed in cancer cells. The E6 oncogene degrades p53 thereby modulating a large set of p53 target genes as shown previously in the cervical carcinoma cell line He...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ben Khalifa, Youcef, Teissier, Sébastien, Tan, Meng-Kwang Marcus, Phan, Quang Tien, Daynac, Mathieu, Wong, Wei Qi, Thierry, Françoise
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2011
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182928/
https://ncbi.nlm.nih.gov/pubmed/21980285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002256
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