Increased betulinic acid induced cytotoxicity and radiosensitivity in glioma cells under hypoxic conditions

BACKGROUND: Betulinic acid (BA) is a novel antineoplastic agent under evaluation for tumor therapy. Because of the selective cytotoxic effects of BA in tumor cells (including gliomas), the combination of this agent with conservative therapies (such as radiotherapy and chemotherapy) may be useful. Pr...

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Detalhes bibliográficos
Main Authors: Bache, Matthias, Zschornak, Martin P, Passin, Sarina, Keßler, Jacqueline, Wichmann, Henri, Kappler, Matthias, Paschke, Reinhard, Kaluđerović, Goran N, Kommera, Harish, Taubert, Helge, Vordermark, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182903/
https://ncbi.nlm.nih.gov/pubmed/21906280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-717X-6-111
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