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The Role of Immune Correlates and Surrogate Markers in the Development of Vaccines and Immunotherapies for Plague
One of the difficulties in developing countermeasures to biothreat agents is the challenge inherent in demonstrating their efficacy in man. Since the first publication of the Animal Rule by the FDA, there has been increased discussion of potential correlates of protection in animal models and their...
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| Formato: | Artigo |
| Idioma: | Inglês |
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Hindawi Publishing Corporation
2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3182760/ https://ncbi.nlm.nih.gov/pubmed/21991451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/365980 |
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