Nontelomeric splice variant of telomere repeat-binding factor 2 maintains neuronal traits by sequestering repressor element 1-silencing transcription factor

Telomere repeat-binding factor 2 (TRF2) is critical for telomere integrity in dividing stem and somatic cells, but its role in postmitotic neurons is unknown. Apart from protecting telomeres, nuclear TRF2 interacts with the master neuronal gene-silencer repressor element 1-silencing transcription fa...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhang, Peisu, Casaday-Potts, Rebecca, Precht, Patricia, Jiang, Haiyang, Liu, Yie, Pazin, Michael J., Mattson, Mark P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2011
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182730/
https://ncbi.nlm.nih.gov/pubmed/21903926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1106906108
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