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Compression and self-entanglement of single DNA molecules under uniform electric field

We experimentally study the effects of a uniform electric field on the conformation of single DNA molecules. We demonstrate that a moderate electric field (∼200 V/cm) strongly compresses isolated DNA polymer coils into isotropic globules. Insight into the nature of these compressed states is gained...

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Библиографические подробности
Главные авторы: Tang, Jing, Du, Ning, Doyle, Patrick S.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182689/
https://ncbi.nlm.nih.gov/pubmed/21911402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105547108
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