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Isolation and characterization of a human telomere.

A method is described that allows cloning of human telomeres in S. cerevisiae by joining human telomeric restriction fragments to yeast artificial chromosome halves. The resulting chimeric yeast-human chromosomes propagate as true linear chromosomes, demonstrating that the human telomere structure i...

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Detalles Bibliográficos
Autores principales: Cheng, J F, Smith, C L, Cantor, C R
Formato: Artigo
Lenguaje:Inglês
Publicado: 1989
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC318265/
https://ncbi.nlm.nih.gov/pubmed/2549507
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